Gene Expression in Failing Hearts Surveyed by High-Density Microarrays

Abstract

Organ-level heart failure can result, most obviously, from the death of cardiac myocytes; such death can occur either acutely (with infarction) or more sporadically (in chronic disease). Both types of death can involve a “cell suicide” pathway known as apoptosis.1 Another key factor for cardiac dysfunction is myocardial fibrosis, which can be, in part, a… (More)

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