Gene Expression Variability within and between Human Populations and Implications toward Disease Susceptibility

@inproceedings{Li2010GeneEV,
  title={Gene Expression Variability within and between Human Populations and Implications toward Disease Susceptibility},
  author={Jingjing Li and Yu Liu and TaeHyung Kim and Martin Renqiang Min and Zhaolei Zhang},
  booktitle={PLoS Computational Biology},
  year={2010}
}
Variations in gene expression level might lead to phenotypic diversity across individuals or populations. Although many human genes are found to have differential mRNA levels between populations, the extent of gene expression that could vary within and between populations largely remains elusive. To investigate the dynamic range of gene expression, we analyzed the expression variability of ∼18, 000 human genes across individuals within HapMap populations. Although ∼20% of human genes show… CONTINUE READING