Gene Expression Profiling of Liver Cancer Stem Cells by RNA-Sequencing

Abstract

BACKGROUND Accumulating evidence supports that tumor growth and cancer relapse are driven by cancer stem cells. Our previous work has demonstrated the existence of CD90(+) liver cancer stem cells (CSCs) in hepatocellular carcinoma (HCC). Nevertheless, the characteristics of these cells are still poorly understood. In this study, we employed a more sensitive… (More)
DOI: 10.1371/journal.pone.0037159

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