Gene Expression Profiling of Human Monocyte-derived Dendritic Cells – Searching for Molecular Regulators of Tolerogenicity

@inproceedings{Schinnerling2015GeneEP,
  title={Gene Expression Profiling of Human Monocyte-derived Dendritic Cells – Searching for Molecular Regulators of Tolerogenicity},
  author={Katina Schinnerling and Paulina A. Garc{\'i}a-Gonz{\'a}lez and Juan Carlos Aguill{\'o}n},
  booktitle={Front. Immunol.},
  year={2015}
}
The ability of dendritic cells (DCs) to initiate and modulate antigen-specific immune responses has made them attractive targets for immunotherapy. Since DC research in humans is limited by the scarcity of DC populations in the blood circulation, most of our knowledge about DC biology and function has been obtained in vitro from monocyte-derived DCs (moDCs), which can be readily generated in sufficient numbers and are able to differentiate into distinct functional subsets depending on the… CONTINUE READING

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