Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction

@inproceedings{Weigt2017GeneEP,
  title={Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction},
  author={S Samuel Weigt and Xiaoyan Wang and Vyacheslav Palchevskiy and Naman Patel and Ariss Derhovanessian and Michael Y Shino and David M Sayah and Aric L Gregson and Joseph Pedulla Lynch and Rajan Saggar and David J. Ross and Abbas A Ardehali and David Elashoff and John A Belperio},
  booktitle={Annals of the American Thoracic Society},
  year={2017}
}
BACKGROUND Chronic Lung Allograft Dysfunction (CLAD) is the main limitation to long-term survival after lung transplantation. Although CLAD is usually not responsive to treatment, earlier identification may improve treatment prospects. METHODS In a nested case control study, 1-year post transplant surveillance bronchoalveolar lavage (BAL) fluid samples were obtained from incipient CLAD (n = 9) and CLAD free (n = 8) lung transplant recipients. Incipient CLAD cases were diagnosed with CLAD… CONTINUE READING