Gene Expression, Intron Density, and Splice Site Strength in Drosophila and Caenorhabditis

@article{Fahey2007GeneEI,
  title={Gene Expression, Intron Density, and Splice Site Strength in Drosophila and Caenorhabditis},
  author={Marie E. Fahey and Desmond G. Higgins},
  journal={Journal of Molecular Evolution},
  year={2007},
  volume={65},
  pages={349-357}
}
In this paper we investigate the relationships among intron density (number of introns per kilobase of coding sequence), gene expression level, and strength of splicing signals in two species: Drosophila melanogaster and Caenorhabditis elegans. We report a negative correlation between intron density and gene expression levels, opposite to the effect previously observed in human. An increase in splice site strength has been observed in long introns in D. melanogaster. We show this is also true… CONTINUE READING

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