Gene Drive Dynamics in Natural Populations: The Importance of Density Dependence, Space, and Sex.

  title={Gene Drive Dynamics in Natural Populations: The Importance of Density Dependence, Space, and Sex.},
  author={Sumit Dhole and Alun L. Lloyd and Fred L. Gould},
  journal={Annual review of ecology, evolution, and systematics},
  volume={51 1},
The spread of synthetic gene drives is often discussed in the context of panmictic populations connected by gene flow and described with simple deterministic models. Under such assumptions, an entire species could be altered by releasing a single individual carrying an invasive gene drive, such as a standard homing drive. While this remains a theoretical possibility, gene drive spread in natural populations is more complex and merits a more realistic assessment. The fate of any gene drive… 

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Gene Drives: Dynamics and Regulatory Matters-A Report from the Workshop "Evaluation of Spatial and Temporal Control of Gene Drives," April 4-5, 2019, Vienna.

  • B. GieseJ. Frieß C. Boëte
  • Environmental Science
    BioEssays : news and reviews in molecular, cellular and developmental biology
  • 2019
Results of the recent workshop on the “Evaluation of Spatial and Temporal Control of Gene Drives” hosted by the Institute of Safety/Security and Risk Sciences in Vienna aimed at gaining some insight into the potential population dynamic behavior of GDs and appropriate measures of control.

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