Gene Drive Dynamics in Natural Populations: The Importance of Density Dependence, Space, and Sex.

@article{Dhole2020GeneDD,
  title={Gene Drive Dynamics in Natural Populations: The Importance of Density Dependence, Space, and Sex.},
  author={Sumit Dhole and Alun L. Lloyd and Fred L. Gould},
  journal={Annual review of ecology, evolution, and systematics},
  year={2020},
  volume={51 1},
  pages={
          505-531
        }
}
The spread of synthetic gene drives is often discussed in the context of panmictic populations connected by gene flow and described with simple deterministic models. Under such assumptions, an entire species could be altered by releasing a single individual carrying an invasive gene drive, such as a standard homing drive. While this remains a theoretical possibility, gene drive spread in natural populations is more complex and merits a more realistic assessment. The fate of any gene drive… 

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