Gene Control by Large Noncoding RNAs

@article{Shamovsky2006GeneCB,
  title={Gene Control by Large Noncoding RNAs},
  author={Ilya Shamovsky and Evgeny Nudler},
  journal={Science's STKE},
  year={2006},
  volume={2006},
  pages={pe40 - pe40}
}
Large noncoding RNAs (lncRNAs) have emerged as key players in regulating various fundamental cellular processes. Recent reports identify a functional lncRNA, Evf-2, that operates during development to control the expression of specific homeodomain proteins, and they provide important insights into the mechanism of cooperation between a newly discovered nuclear receptor co-repressor protein (SLIRP) and steroid receptor activator RNA. Evf-2 is the first example of lncRNA directly involved in… 
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