Gene Composer in a structural genomics environment

               Gene Composer in a structural genomics environment},
  author={Don Lorimer and Amy C. Raymond and Mark B. Mixon and Alex B. Burgin and Bart L. Staker and Lance J. Stewart},
  booktitle={Acta crystallographica. Section F, Structural biology and crystallization communications},
The structural genomics effort at the Seattle Structural Genomics Center for Infectious Disease (SSGCID) requires the manipulation of large numbers of amino-acid sequences and the underlying DNA sequences which are to be cloned into expression vectors. To improve efficiency in high-throughput protein structure determination, a database software package, Gene Composer, has been developed which facilitates the information-rich design of protein constructs and their underlying gene sequences. With… CONTINUE READING