Gender susceptibility to chronic hepatitis C virus infection associated with interleukin 10 promoter polymorphism.

@article{Paladino2006GenderST,
  title={Gender susceptibility to chronic hepatitis C virus infection associated with interleukin 10 promoter polymorphism.},
  author={Natalia Paladino and Hugo A Fainboim and G. del Carmen Theiler and Teresa Schroder and Alberto Eduardo Mu{\~n}oz and Ana Claudia Flores and Omar Andr{\'e}s Galdame and Leonardo Fainboim},
  journal={Journal of virology},
  year={2006},
  volume={80 18},
  pages={9144-50}
}
Elevated levels of interleukin 10 (IL-10) were previously described for chronically hepatitis C virus (HCV)-infected patients. We determined by a sequence-specific oligonucleotide probing technique the IL-10 promoter genotypes in 286 Argentinean HCV patients grouped according to disease outcome. The GG genotype (position -1082) is known to be associated with high IL-10 production, GA is considered an intermediate producer, and AA is associated with low IL-10 production. We found an increase in… CONTINUE READING
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ROLE OF IL-10 IN GENDER SUSCEPTIBILITY TO HCV 9149 on S etem er 22, 2017 by gest http/jvi.asm .rg/ D ow nladed fom

  • D. R. Nelson, Z. Tu, C. Soldevila-Pico, M. Abdelmalek, H. Zhu, R.Y.L. Xu
  • Hepatology
  • 2006
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