Gender-related differences and similarities in eligibility for coronary reperfusion and outcome after out-of-hospital cardiac arrest

Abstract

Results 1817 patients were included (520 women, 29%). Women were older than men (62.8 vs 59.1 years, P < 0.0001), with less cardiomyopathy. They had less frequently bystander cardiopulmonary resuscitation (84% vs 88%, P < 0.05) and less shockable rhythm (42% vs 61%, P < 0.001). After multivariate logistic regression, male sex was associated with the decision to perform coronary angiography (OR 1.73, 95%CI 1.28-2.34, P < 0.001) and results were consistent even after propensity-score matching (P = 0.02). Among 1157 patients who underwent coronary angiography, rate of PCI did not differ between men and women (OR 1.30, 95%CI 0.90 1.88, P = 0.17). Results after matching (211 men, 211 women) were consistent (P = 0.13). PCI was associated with favorable outcome by multivariate logistic regression (OR = 1.45, 95%IC = 1.07 1.96, P = 0.02) with no interaction between gender and PCI (P for interaction = 0.40). Association between PCI and outcome was consistent across genders.

DOI: 10.1186/2197-425X-3-S1-A193

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Cite this paper

@inproceedings{Bougouin2015GenderrelatedDA, title={Gender-related differences and similarities in eligibility for coronary reperfusion and outcome after out-of-hospital cardiac arrest}, author={Wulfran Bougouin and Florence Falconetti Dumas and Eloi Marijon and Guillaume Geri and B Champigneulle and J D Chiche and Olivier Varenne and Christian M Spaulding and Jean - Paul Mira and Xavie Jouven and Alain Cariou}, booktitle={Intensive care medicine experimental}, year={2015} }