Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain

@article{Taylor1999GenderinfluencedOQ,
  title={Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain},
  author={Benjamin A. Taylor and Lisa M. Tarantino and Sandra J. Phillips},
  journal={Mammalian Genome},
  year={1999},
  volume={10},
  pages={963-968}
}
Abstract. The inheritance of adiposity and related traits has been investigated in the obese, diabetes-prone KK/HlLt (KK) and the lean, normoglycemic C57BL/6J (B6) mouse strains, their F1 hybrids, and a large intercross generation. Adiposity index (AI) was defined as the sum of four fat depot weights divided by body weight. Both male and female KK mice were obese, but AI values averaged twofold higher in females than in males. In contrast, B6 females were slightly more lean than males. A genome… CONTINUE READING

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HIGHLY INFLUENTIAL