Gender dimorphic tissue perfusion response after acute hemorrhage and resuscitation: role of vascular endothelial cell function.

Abstract

Proestrous female rodents are protected from the deleterious effects of trauma-hemorrhage that are observed in males. We hypothesized that the gender dimorphic outcome after trauma-hemorrhage might be related to gender differences in endothelial function and organ perfusion under such conditions. Male and cycle-matched proestrous female Sprague-Dawley rats… (More)

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