Gender differences in the relationship between leptin, insulin resistance and the autonomic nervous system

@article{Flanagan2007GenderDI,
  title={Gender differences in the relationship between leptin, insulin resistance and the autonomic nervous system},
  author={Daniel E Flanagan and Julian C Vaile and Graham W Petley and David W. Phillips and Jeffrey S Robinson},
  journal={Regulatory Peptides},
  year={2007},
  volume={140},
  pages={37-42}
}
OBJECTIVES Leptin, an important hormonal regulator of body weight, has been shown to stimulate the sympathetic nervous system (SNS) in vitro although the physiological relevance remains unclear. Increased SNS activity has been implicated in the pathogenesis of insulin resistance and an increased cardiovascular risk. We have therefore investigated the relationship between leptin, insulin resistance and cardiac autonomic activity in healthy young adults. 130 healthy men and women age 20.9 years… CONTINUE READING

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