Gender differences in stimulated cytokine production following acute psychological stress

@article{Prather2009GenderDI,
  title={Gender differences in stimulated cytokine production following acute psychological stress},
  author={Aric A. Prather and Judith E. Carroll and Jacqueline M. Fury and Kevin K McDade and Diana C. Ross and Anna L. Marsland},
  journal={Brain, Behavior, and Immunity},
  year={2009},
  volume={23},
  pages={622-628}
}
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76 Citations
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Healthy, post-menopausal females exhibit substantially greater IL-6 responses to acute stress, which if sustained over time may have clinical implications for the development and maintenance of inflammatory-related conditions prevalent in older women.
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Sex differences in the relationships between inflammatory and socioemotional responses to an inflammatory challenge may be particularly important for understanding why females are two times as likely as males to develop depressive disorders.
Sex Differences in the Inflammatory Consequences of Stress: Implications for Pharmacotherapy
TLDR
The studies reviewed herein strongly support the need for further studies to elucidate whether females are especially sensitive to anti-inflammatory compounds as adjuvants to traditional therapies, and propose a locus coeruleus–norepinephrine–cytokine circuit as a conduit through which stress could increase stress susceptibly in females.
Lipopolysaccharide-binding protein and leptin are associated with stress-induced interleukin-6 cytokine expression ex vivo in obesity.
TLDR
Results showed that obese subjects elicited a greater LPS-induced IL-6 along with its mRNA expression following mental stress compared to normal-weight subjects, consistent with the idea that endogenous inflammatory agents, often elevated with obesity, enhance inflammatory responses to psychological stress.
Effect of Gender and Menstrual Cycle on Immune System Response to Acute Mental Stress: Apoptosis as a Mediator
TLDR
Although a correlation was not found between immune system changes and NO levels, glucocorticoids seem to have a role in the observed differences and sex steroids affect the pattern of stress-related immune cell distribution.
Cytokine secretion responsiveness of lymphomonocytes following cortisol cell exposure: Sex differences
TLDR
It is highlighted that cortisol differently affects male and female lymphomonocytes, shifting the cytokine release in favour of a pro-inflammatory pattern in male cells and an anti-inflammatory secretion profile in female cells, opening the way to study the influences of other stressful factors involved in the neurohumoral changes occurring in the response to stress conditions.
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References

SHOWING 1-10 OF 52 REFERENCES
Clinical Depression and Regulation of the Inflammatory Response During Acute Stress
TLDR
It is suggested that under acutely challenging conditions, depression is associated with greater resistance to molecules that normally terminate the inflammatory cascade and an impaired capacity to regulate inflammation could underlie some of the excess morbidity and mortality that has been associated with depression.
Sex Differences in Glucocorticoid Sensitivity of Proinflammatory Cytokine Production After Psychosocial Stress
TLDR
Investigating the impact of psychosocial stress and HPA axis activation on the GC sensitivity of proinflammatory cytokine production in men and women demonstrates that despite similar free cortisol responses of men andWomen (studied in the luteal phase of their menstrual cycle) to psychossocial stress, gender may exert differential effects on the immune system by modulating GC sensitivity.
Stress-induced changes in LPS-induced pro-inflammatory cytokine production in chronic fatigue syndrome
Delayed response and lack of habituation in plasma interleukin-6 to acute mental stress in men
Stimulated production of interleukin-8 covaries with psychosocial risk factors for inflammatory disease among middle-aged community volunteers
Increases in stimulated secretion of proinflammatory cytokines by blood monocytes following arousal of negative affect: The role of insulin resistance as moderator
Acute mental stress elicits delayed increases in circulating inflammatory cytokine levels.
TLDR
It is indicated that inflammatory cytokines respond to acute mental stress in humans with delayed increases, and suggest that individual differences in cytokine responses are associated with sympathetic reactivity.
The effects of acute psychological stress on circulating inflammatory factors in humans: A review and meta-analysis
The Relation of Severity of Depressive Symptoms to Monocyte-Associated Proinflammatory Cytokines and Chemokines in Apparently Healthy Men
Objective We examined the relation of severity of depressive symptoms to lipopolysaccharide-stimulated expression of monocyte-associated proinflammatory cytokines and chemokines in 53 nonsmoking,…
Impact of oral contraceptive use on glucocorticoid sensitivity of pro-inflammatory cytokine production after psychosocial stress
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