Gender differences in pharmacokinetics of tacrolimus and their clinical significance in kidney transplant recipients.

@article{VelikoviRadovanovi2011GenderDI,
  title={Gender differences in pharmacokinetics of tacrolimus and their clinical significance in kidney transplant recipients.},
  author={Radmila M. Veli{\vc}kovi{\'c}-Radovanovi{\'c} and Momir Mikov and Goran J. Paunovic and Vidojko Djordjevi{\'c} and M Roksanda Stojanovic and Tatjana Cvetkovi{\'c} and Aleksandra Cati{\'c}- Djordjevi{\'c}},
  journal={Gender medicine},
  year={2011},
  volume={8 1},
  pages={
          23-31
        }
}
BACKGROUND The possible influence of gender on tacrolimus disposition and response in kidney transplant recipients is an issue of medical importance. OBJECTIVE The aim of this study was to detect interpatient pharmacokinetic variability of tacrolimus due to patients' gender and to assess the predictability of individual tacrolimus concentrations using abbreviated AUC measurements. The secondary objective was to find the best sampling time to predict the exposure of tacrolimus in kidney… CONTINUE READING
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