Gender differences in counterregulation to hypoglycaemia

  title={Gender differences in counterregulation to hypoglycaemia},
  author={Stephanie A. Amiel and Alberto Maran and Jake K Powrie and A. Margot Umpleby and Ian Macdonald},
To investigate the effect of gender on catecholamine responses to hypoglycaemia, single-step euglycaemic-hypoglycaemic clamps have been performed in 14 healthy men and 17 women. Adrenaline responses were 44% lower in females (p<0.01) and noradrenaline 17% lower (p=0.08). In response to low-dose intravenous insulin infusion (0.3 mU · kg−1 · min−1), plasma glucose fall and counter-regulation in seven men and seven women had a different course (p<0.001), with different glucose kinetics. In men… CONTINUE READING

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