Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro: dexamethasone and estradiol stimulate leptin release in women, but not in men.

@article{Casabiell1998GenderDI,
  title={Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro: dexamethasone and estradiol stimulate leptin release in women, but not in men.},
  author={Xes{\'u}s Casabiell and Ver{\'o}nica Pi{\~n}eiro and Roberto Pein{\'o} and Mary Lage and Jes{\'u}s P. Cami{\~n}a and Rosal{\'i}a Gallego and L. I. Gonzalez de Vallejo and Carlos Di{\'e}guez and Felipe F F Casanueva},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1998},
  volume={83 6},
  pages={2149-55}
}
Leptin is a hormone secreted by the adipocytes to serve as a signal to the central nervous system to regulate energy homeostasis. Circulating leptin mainly reflects both total fat mass and the size of constituent adipocytes, although other ancillary hormonal factors may contribute to its blood concentration. Relevant gender differences in leptin concentrations have been reported, but it is not clear whether the elevated leptin levels in women are an intrinsic property of their adipocytes or… CONTINUE READING
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