Gender differences in apoptotic signaling in heart failure due to volume overload

@article{Dent2009GenderDI,
  title={Gender differences in apoptotic signaling in heart failure due to volume overload},
  author={Melissa Robin. Dent and Paramjit S Tappia and Naranjan Singh Dhalla},
  journal={Apoptosis},
  year={2009},
  volume={15},
  pages={499-510}
}
This study examined sex differences in the regulation of pro- and anti-apoptotic proteins in cardiac hypertrophy and heart failure due to volume overload induced by arteriovenous (AV) shunt in rats. General characteristics and hemodynamic assessment revealed the presence of cardiac hypertrophy at 4 weeks of AV shunt in male (n = 12) and female (n = 12) rats, whereas heart failure was seen at 16 weeks in male rats only. Although a decrease in apoptosis was seen in hearts of both sexes at 4 weeks… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 44 REFERENCES

Influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats

  • J Ren
  • Clin Exp Pharmacol Physiol 34:432–438
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…