Gender difference of androgen actions on skeletal muscle transcriptome.

@article{Yoshioka2007GenderDO,
  title={Gender difference of androgen actions on skeletal muscle transcriptome.},
  author={Mayumi Yoshioka and Andr{\'e} Boivin and Carl R. Bolduc and Jonny St-Amand},
  journal={Journal of molecular endocrinology},
  year={2007},
  volume={39 2},
  pages={
          119-33
        }
}
Sarcopenia is related to metabolic syndrome in postmenopausal women. Hormone replacement therapies with androgens improve muscle functions by molecular mechanisms that are still unknown, at least partly because the skeletal muscle transcriptome has been less characterized in females. We performed the serial analysis of gene expression method in six experimental groups, intact (male and female), ovariectomy (OVX), OVX+dihydrotestosterone (DHT) injection 1, 3, or 24 h before kill in mice. The 438… CONTINUE READING

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