Gender difference in the miotic potency of soman vapor in rats.

  title={Gender difference in the miotic potency of soman vapor in rats.},
  author={P A Dabisch and Michael S. Horsmon and James T Taylor and William T. Muse and D. Brooke Miller and Douglas R. Sommerville and Robert J. Mioduszewski and Sandra A Thomson},
  journal={Cutaneous and ocular toxicology},
  volume={27 2},
The present study was undertaken to investigate the miotic potency of soman vapor in the rat, as well as gender differences in the miotic response to soman vapor that have been reported previously for other nerve agents. The results of the present study demonstrate that the miotic potency of soman vapor is significantly less than that of other nerve agents, and that female rats are 2.5-3.0 times more sensitive to soman vapor than male rats. The results also demonstrate that ocular… CONTINUE READING

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