Gender-based profiles of developmental immunotoxicity to lead in the rat: assessment in juveniles and adults.

@article{Bunn2001GenderbasedPO,
  title={Gender-based profiles of developmental immunotoxicity to lead in the rat: assessment in juveniles and adults.},
  author={Terry Lee Bunn and Patrick J. Parsons and Elizabeth Vaquera Grace Kao and Rodney Dietert},
  journal={Journal of toxicology and environmental health. Part A},
  year={2001},
  volume={64 3},
  pages={223-40}
}
Gender-based differences in immunotoxicity induced by the heavy metal lead (Pb) have been observed both in the juvenile chicken and the adult rat following low-level exposure during embryonic development. To better define the gender-based differences, as related to dose following in utero exposure to Pb, potential differential sensitivities were examined after exposure of F344 rats to low concentrations of Pb (0, 50, 100, or 250 ppm Pb) ad libitum throughout gestation. Immune assessment was… CONTINUE READING
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