Gender-based differences in cardiac repolarization in mouse ventricle.

@article{TrpanierBoulay2001GenderbasedDI,
  title={Gender-based differences in cardiac repolarization in mouse ventricle.},
  author={V{\'e}ronique Tr{\'e}panier-Boulay and Chantale St-Michel and Annie M Tremblay and C{\'e}line Fiset},
  journal={Circulation research},
  year={2001},
  volume={89 5},
  pages={437-44}
}
The mouse heart has become a widely used model for genetic studies of heart diseases. Thus, understanding gender differences in mouse cardiac repolarization is crucial to the interpretation of such studies. The objective of this study was to evaluate whether there are gender differences in cardiac repolarization in mouse ventricle and to gain insights into the ionic and molecular mechanisms underlying these differences. Action potential durations (APDs) and K(+) currents in male and female… CONTINUE READING

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