Gender aspects in chronic myeloid leukemia: long-term results from randomized studies

@article{Berger2005GenderAI,
  title={Gender aspects in chronic myeloid leukemia: long-term results from randomized studies},
  author={U. Berger and Ole Maywald and Markus Pfirrmann and Tanja Lahaye and Andreas Hochhaus and A. Reiter and J. Hasford and Hermann Heimpel and Dieter Kurt Hossfeld and H. J. Kolb and Helmut L{\"o}ffler and H. B. Pralle and Wolfgang Queisser and Rȕdiger Hehlmann},
  journal={Leukemia},
  year={2005},
  volume={19},
  pages={984-989}
}
Gender-related aspects in chronic myeloid leukemia (CML) have not been studied well. We therefore analyzed 856 patients with Ph/BCR-ABL-positive CML from the German randomized CML-studies I (interferon α (IFN) vs hydroxyurea (HU) vs busulfan) and II (IFN+HU vs HU alone). The median observation time was 8.6 years. A total of 503 patients (59%) were male. Female patients were older (51 vs 46 years; P<0.0001), presented with lower hemoglobin (11.7 vs 12.5 g/dl; P<0.0001), higher platelet counts… CONTINUE READING