Gender and gonadal status differences in zona reticularis expression in marmoset monkey adrenals: Cytochrome b5 localization with respect to cytochrome P450 17,20-lyase activity.

@article{Pattison2007GenderAG,
  title={Gender and gonadal status differences in zona reticularis expression in marmoset monkey adrenals: Cytochrome b5 localization with respect to cytochrome P450 17,20-lyase activity.},
  author={J Christina Pattison and Wendy Saltzman and David H. Abbott and Brynn K Hogan and Ann D. Nguyen and Bettina Husen and Almuth Einspanier and Alan James Conley and Ian M. Bird},
  journal={Molecular and cellular endocrinology},
  year={2007},
  volume={265-266},
  pages={93-101}
}
Neonatal marmosets express an adrenal fetal zone comparable to humans. While adult males fail to express a functional ZR, with barely detectable blood DHEA levels, females produce higher levels of DHEA than males in adulthood. We investigated the presence of a putative functional ZR in adult female marmosets. In contrast to males, immunohistochemical analysis showed the ZR marker cytochrome b5 was elevated in the innermost zone in cycling females (compared to testis-intact males), further… CONTINUE READING

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