Gender-Specific Hierarchy in Nuage Localization of PIWI-Interacting RNA Factors in Drosophila


PIWI-interacting RNAs (piRNAs) are germline-specific small non-coding RNAs that form piRNA-induced silencing complexes (piRISCs) by associating with PIWI proteins, a subclade of the Argonaute proteins predominantly expressed in the germline. piRISCs protect the integrity of the germline genome from invasive transposable DNA elements by silencing them… (More)
DOI: 10.3389/fgene.2011.00055


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