Gender Effects on Association of Serotonin Transporter Gene Polymorphism with Symptoms of Central Fatigue

@article{Maluchenko2009GenderEO,
  title={Gender Effects on Association of Serotonin Transporter Gene Polymorphism with Symptoms of Central Fatigue},
  author={Natalia V Maluchenko and J. V. Schegolkova and Maria A Kulikova and Marina A Timofeeva and V. A. Shlepcova and Olga V. Sysoeva and Alexandr G Tonevitsky},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2009},
  volume={147},
  pages={462-465}
}
In order to test the “serotonin” hypothesis of the genesis of central fatigue, we studied association between genotype and fatigue (3-hour mental workload consisting of information processing and logical task solution) using analysis of variance for different indices (well-being, activity, mood, mental fatigue index). It was concluded that young men with serotonin deficit (LL genotype) and girls with serotonin excess (S genotype) were less tolerant to long-lasting mental workload. Thus, we… CONTINUE READING