Gemfibrozil also corrects dyslipidemia in postmenopausal women and smokers.

@article{Koskinen1992GemfibrozilAC,
  title={Gemfibrozil also corrects dyslipidemia in postmenopausal women and smokers.},
  author={Petri K. Koskinen and Petri T. Kovanen and Jaakko Tuomilehto and Vesa Manninen},
  journal={Archives of internal medicine},
  year={1992},
  volume={152 1},
  pages={90-6}
}
We compared the efficacy of three formulations and two dosage regimens of gemfibrozil in 322 dyslipidemic (non-high-density lipoprotein [HDL] cholesterol level, greater than or equal to 5.2 mmol/L [greater than or equal to 200 mg/dL]) middle-aged male and postmenopausal female patients in a 1-year open-label trial. Of the patients studied, 109 received the standard 1200-mg dose of gemfibrozil, ie, two 300-mg capsules twice daily; 107 received one 600-mg tablet twice daily; and 106 received a… CONTINUE READING

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The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
Of the patients studied , 109 received the standard 1200-mg dose of gemfibrozil , ie , two 300-mg capsules twice daily ; 107 received one 600-mg tablet twice daily ; and 106 received a single dose of 900 mg of gemfibrozil in two 450-mg tablets in the evening .
Of the patients studied , 109 received the standard 1200-mg dose of gemfibrozil , ie , two 300-mg capsules twice daily ; 107 received one 600-mg tablet twice daily ; and 106 received a single dose of 900 mg of gemfibrozil in two 450-mg tablets in the evening .
LipoproteinsIs chemical classification of gene productApolipoproteins A
The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
The three treatment groups showed equal changes in each lipoprotein measure studied , ie , in serum levels of triglycerides , total cholesterol , low - density lipoprotein and HDL cholesterol , HDL subfractions HDL2 and HDL3 , and apolipoproteins A - I , A - II , and B. When the therapeutic responses were analyzed separately in men ( n = 219 ) and women ( n = 103 ) , significantly greater decreases in serum levels of total triglycerides , low - density lipoprotein cholesterol , and apolipoprotein B , and a significantly greater increase in HDL3 cholesterol level and apolipoprotein A - I / B ratio , were seen in the women .
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