Gelsolin amyloidosis: genetics, biochemistry, pathology and possible strategies for therapeutic intervention.

Abstract

Protein misassembly into aggregate structures, including cross-β-sheet amyloid fibrils, is linked to diseases characterized by the degeneration of post-mitotic tissue. While amyloid fibril deposition in the extracellular space certainly disrupts cellular and tissue architecture late in the course of amyloid diseases, strong genetic, pathological and… (More)
DOI: 10.3109/10409238.2012.661401

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics