Gelsolin: a candidate for suppressor of human bladder cancer.

@article{Tanaka1995GelsolinAC,
  title={Gelsolin: a candidate for suppressor of human bladder cancer.},
  author={Masamitsu Tanaka and Leonhard M{\"u}llauer and Yasunari Ogiso and Hiroshi Fujita and Setsuko Moriya and Keiji Furuuchi and Touru Harabayashi and Nobuo Shinohara and Tomohiko Koyanagi and Noboru Kuzumaki},
  journal={Cancer research},
  year={1995},
  volume={55 15},
  pages={3228-32}
}
Human transitional cell carcinomas of the bladder frequently reveal chromosomal abnormalities that span a range between chromosome 9p12 and 9qter, even at early stages of bladder carcinogenesis. Because the gene that encodes an actin-regulatory protein, gelsolin, is localized in chromosome 9q33, we examined the expression of gelsolin in a number of human bladder cancer cell lines and tissues. In all 6 cell lines and in 14 of the 18 tumor tissues (77.8%), gelsolin expression was undetectable or… CONTINUE READING
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