Gelatinases promote calcification of vascular smooth muscle cells by up-regulating bone morphogenetic protein-2.


Matrix metalloproteinase-2 (MMP-2), also known as gelatinase A, is involved in vascular calcification. Another member of gelatinases is MMP-9 (gelatinase B). However, the role of gelatinases in the pathogenesis of vascular calcification is not well understood. The current study aims to clarify the relationship between gelatinases and vascular calcification… (More)
DOI: 10.1016/j.bbrc.2016.01.067


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