Gelatinases and their tissue inhibitors in ovarian tumors; TIMP-1 is a predictive as well as a prognostic factor.

@article{Rauvala2005GelatinasesAT,
  title={Gelatinases and their tissue inhibitors in ovarian tumors; TIMP-1 is a predictive as well as a prognostic factor.},
  author={Marita Rauvala and Ulla S Puistola and Taina Turpeenniemi-Hujanen},
  journal={Gynecologic oncology},
  year={2005},
  volume={99 3},
  pages={656-63}
}
OBJECTIVE In the present study, the significance of circulating matrix metalloproteinases -2 and -9 (MMP-2, MMP-9), as well as their tissue inhibitors -1 and -2 (TIMP-1, TIMP-2) in ovarian cancer were studied to assess the possibility of using them in clinical decision-making. METHODS We measured, prior to primary surgery, the concentrations of these proteins in serum samples of 115 patients with an ovarian tumor: 63 with cancer, 6 with a low malignant potential tumor, and 46 with a benign… CONTINUE READING
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