Gel Electrophoresis of RNA in Denaturing Formaldehyde Agarose Gels

@inproceedings{Southern2003GelEO,
  title={Gel Electrophoresis of RNA in Denaturing Formaldehyde Agarose Gels},
  author={Edwin M. Southern},
  year={2003}
}
Formaldehyde reacts with RNA, and when RNA is heated in the presence of formaldehyde all secondary structures are removed. Hence, gel electrophoresis of RNA in agarose gels containing formaldehyde provides a good denaturing gel system. Keywords: denaturing; electrophoresis; RNA; agarose; formaldehyde