Gefitinib induces apoptosis in human glioma cells by targeting Bad phosphorylation

Abstract

Gefitinib, a selective epidermal growth factor receptor tyrosine kinase inhibitor, is under clinical testing and use in cancer patients, including glioma. However, the molecular mechanisms involved in gefitinib-mediated anticancer effects against glioma remain largely uncharacterized. Gefitinib inhibits cell growth and induces apoptosis in human glioma… (More)
DOI: 10.1007/s11060-011-0632-3

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@article{Chang2011GefitinibIA, title={Gefitinib induces apoptosis in human glioma cells by targeting Bad phosphorylation}, author={Cheng-Yi Chang and Chiung-Chyi Shen and Hong-Lin Su and Chun-Jung Chen}, journal={Journal of Neuro-Oncology}, year={2011}, volume={105}, pages={507-522} }