Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo-2 colon cancer cell line in vitro.

@article{Uddin2007GeduninAL,
  title={Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo-2 colon cancer cell line in vitro.},
  author={Shaikh Jamal Uddin and Lutfun Nahar and Jamil A Shilpi and Mohammad Shoeb and Tomasz Borkowski and Simon Gibbons and Moira Middleton and Maureen Byres and Satyajit D Sarker},
  journal={Phytotherapy research : PTR},
  year={2007},
  volume={21 8},
  pages={757-61}
}
Xylocarpus granatum J. König (Meliaceae), commonly known as 'dhundul', is a Bangladeshi mangrove tree, and well distributed in a number of other countries of south-east Asia, Australia and east Africa. Traditionally, X. granatum has been used as an astringent and febrifuge, and also for the treatment of fever, malaria, thrush, cholera, dysentery and diarrhoea in many countries including Bangladesh. Two limonoids, gedunin and 1alpha-hydroxy-1,2-dihydrogedunin, the latter being new, have been… CONTINUE READING

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