Gating of TRP channels: a voltage connection?

@article{Nilius2005GatingOT,
  title={Gating of TRP channels: a voltage connection?},
  author={Bernd Nilius and Karel Talavera and Grzegorz Owsianik and Jean Prenen and Guy Droogmans and Thomas Voets},
  journal={The Journal of physiology},
  year={2005},
  volume={567 Pt 1},
  pages={
          35-44
        }
}
TRP channels represent the main pathways for cation influx in non-excitable cells. Although TRP channels were for a long time considered to be voltage independent, several TRP channels now appear to be weakly voltage dependent with an activation curve extending mainly into the non-physiological positive voltage range. In connection with this voltage dependence, there is now abundant evidence that physical stimuli, such as temperature (TRPV1, TRPM8, TRPV3), or the binding of various ligands… CONTINUE READING
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