Gating and Conduction Properties of a Sodium-activated Cation Channel from Lobster Olfactory Receptor Neurons

@article{Zhainazarov1997GatingAC,
  title={Gating and Conduction Properties of a Sodium-activated Cation Channel from Lobster Olfactory Receptor Neurons},
  author={Asylbek B. Zhainazarov and Barry W. Ache},
  journal={The Journal of Membrane Biology},
  year={1997},
  volume={156},
  pages={173-190}
}
The gating and conduction properties of a channel activated by intracellular Na+ were studied by recording unitary currents in inside-out patches excised from lobster olfactory receptor neurons. Channel openings to a single conductance level of 104 pS occurred in bursts. The open probability of the channel increased with increasing concentrations of Na+. At 210 mm Na+, membrane depolarization increased the open probability e-fold per 36.6 mV. The distribution of channel open times could be fit… CONTINUE READING