Gatekeepers of intestinal inflammation

@article{Arnett2009GatekeepersOI,
  title={Gatekeepers of intestinal inflammation},
  author={Heather A. Arnett and Joanne L. Viney},
  journal={Inflammation Research},
  year={2009},
  volume={59},
  pages={1-14}
}
The intestine is subjected to a barrage of insults from food, bacterial flora, and pathogens. Despite this constant antigenic challenge, the mucosal tissues lining the intestinal tract remain largely under control. The mechanisms regulating the homeostatic balance in the gut have been investigated for many years by many groups, but the precise nature of the regulatory control remains elusive. In this review, we provide an overview of pathways proposed to be involved in dampening the… CONTINUE READING

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