Gastroretentive Orlistat Microspheres: Formulation, Characterization, and In Vitro Evaluation

Abstract

The present study involves the preparation and evaluation of floating microspheres of orlistat for improving drug bioavailability by prolongation of gastric residence time. The microspheres were prepared by a solvent diffusion–evaporation technique using inert polymers (Eudragit RL100, cellulose acetate, and ethyl cellulose). The effect of three formulation… (More)

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@inproceedings{Sateesha2011GastroretentiveOM, title={Gastroretentive Orlistat Microspheres: Formulation, Characterization, and In Vitro Evaluation}, author={SB. Sateesha and B. Prakash Rao and AJ. Rajamma and V. G. Nargund}, year={2011} }