Gastroprotective effects of ethanolic extract from Cissampelos pareira in experimental animals

  title={Gastroprotective effects of ethanolic extract from Cissampelos pareira in experimental animals},
  author={Gupta Amresh and Hussain Zeashan and Ram Ji Gupta and Ravi Kant and Chandana Venkateswara Rao and Paras Nath Singh},
  journal={Journal of Natural Medicines},
Ethanolic extract of Cissampelos pareira (L.) Hirsuta (Menispermaceae) roots have been examined in various acute and chronic ulcers in validated experimental models in rats. C. pareira extract of 25–100 mg/kg administered orally, twice daily for 5 days showed a dose-dependent, ulcer-protective effect. The extract demonstrated significant protection against 100% ethanol- (P < 0.05), aspirin- (P < 0.001), cold-restraint stress- (P < 0.01) and pylorus ligation- (P < 0.001) induced acute gastric… CONTINUE READING


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