Gastroprotective effect of leukotriene receptor blocker montelukast in alendronat-induced lesions of the rat gastric mucosa.

Abstract

Alendronate causes serious gastrointestinal adverse effects. We aimed to investigate if montelukast, a leukotriene receptor antagonist, is protective against this damage. Rats were administered 20 mg/kg alendronate by gavage for 4 days, either alone or following treatment with montelukast (10 mg/kg). On the last day, following drug administration, pilor… (More)

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Cite this paper

@article{ener2005GastroprotectiveEO, title={Gastroprotective effect of leukotriene receptor blocker montelukast in alendronat-induced lesions of the rat gastric mucosa.}, author={G{\"{o}ksel Şener and Caner Kapucu and Şule Çetinel and Esra Çikler and G. Ayanoglu-d{\"{u}lger}, journal={Prostaglandins, leukotrienes, and essential fatty acids}, year={2005}, volume={72 1}, pages={1-11} }