• Corpus ID: 44041563

Gastroprotective effect of Phyllanthus niruri leaf extract against ethanolinduced ethanolinduced ethanolinduced gastric mucosal injury in rats

  title={Gastroprotective effect of Phyllanthus niruri leaf extract against ethanolinduced ethanolinduced ethanolinduced gastric mucosal injury in rats},
  author={Mahmood Ameen Abdulla and Khaled Abdul-Aziz Ahmed and Fouad Al-Bayaty and Yaghma Masood},
The main objective of this study is to evaluate the gastroprotective activity of the Phyllanthus niruri leaf extract against ethanol-induced gastric mucosal injury in rats. Six groups of Wistar rats were pretreated, respectively, with distilled water; omeprazole 20 mg/kg; and 250, 500, 750 and 1000 mg/kg P. niruri leaf extract 30 min before oral administration of absolute ethanol to generate gastric mucosal injury. After one hour later, the rats were sacrificed and the ulcer areas of the… 

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