Gastroprotective effect of Phyllanthus niruri leaf extract against ethanolinduced ethanolinduced ethanolinduced gastric mucosal injury in rats

@inproceedings{Abdulla2010GastroprotectiveEO,
  title={Gastroprotective effect of Phyllanthus niruri leaf extract against ethanolinduced ethanolinduced ethanolinduced gastric mucosal injury in rats},
  author={Mahmood Ameen Abdulla and Khaled Abdul-Aziz Ahmed and F. Al-bayaty and Yaghma Masood},
  year={2010}
}
The main objective of this study is to evaluate the gastroprotective activity of the Phyllanthus niruri leaf extract against ethanol-induced gastric mucosal injury in rats. Six groups of Wistar rats were pretreated, respectively, with distilled water; omeprazole 20 mg/kg; and 250, 500, 750 and 1000 mg/kg P. niruri leaf extract 30 min before oral administration of absolute ethanol to generate gastric mucosal injury. After one hour later, the rats were sacrificed and the ulcer areas of the… CONTINUE READING

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