Gastroprotective activity of the chloroform extract of the roots from Arctium lappa L.

  title={Gastroprotective activity of the chloroform extract of the roots from Arctium lappa L.},
  author={Ana Carolina D Dos Santos and Cristiane Hatsuko Baggio and Cristina Setim Freitas and Juliana Lepieszynski and B{\'a}rbara Mayer and Andr{\'e} Twardowschy and Fabiana Cristina Missau and {\'E}lide Pereira dos Santos and Moacir Geraldo Pizzolatti and Maria Consuelo Andrade Marques},
  journal={The Journal of pharmacy and pharmacology},
  volume={60 6},
Arctium lappa L. is used in folk medicine as a diuretic, depurative and digestive stimulant and in dermatological conditions. The objective of this study was to evaluate the effect and the possible mechanisms involved in the gastroprotective effects of a chloroform extract (CE) of the roots from A. lappa and its fractions. Oral pretreatment with CE (10, 30 and 100 mg kg(-1)) significantly reduced gastric lesions induced by ethanol by 61%, 70% and 76%, respectively. Oral administration of CE… CONTINUE READING


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