• Corpus ID: 29711185

Gastroprotective activity of caryophyllene oxide: the role of nitric oxide, prostaglandins and sulfhydryls.

  title={Gastroprotective activity of caryophyllene oxide: the role of nitric oxide, prostaglandins and sulfhydryls.},
  author={Mar{\'i}a Elena S{\'a}nchez-Mendoza and Leticia Cruz-Antonio and Mar{\'i}a Guadalupe Cupido-S{\'a}nchez and Guillermo Garc{\'i}a-Castillo and Jes{\'u}s Arrieta},
  journal={journal of applied pharmaceutical science},
Article history: Received on: 14/08/2014 Revised on: 27/08/2014 Accepted on: 11/09/2014 Available online: 27/09/2014 The present study was carried out to evaluate the gastroprotective effect of caryophyllene oxide, and investigate the gastroprotective mechanism. For this purpose, Wistar rats received vehicle, caryophyllene oxide (10-100 mg/kg) or carbenoxolone (1-100 mg/kg, used as the reference drug). Thirty minutes later absolute ethanol was given orally, and 2 h later the stomach was… 

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