Gastrointestinal tract protein synthesis and mRNA levels for proteolytic systems in adult fasted rats.

@article{Samuels1996GastrointestinalTP,
  title={Gastrointestinal tract protein synthesis and mRNA levels for proteolytic systems in adult fasted rats.},
  author={Susan E. Samuels and Daniel Taillandier and Eveline Aurousseau and Yves Cherel and Yvon le Maho and M L Arnal and Didier Attaix},
  journal={The American journal of physiology},
  year={1996},
  volume={271 2 Pt 1},
  pages={E232-8}
}
We studied protein turnover in the gastrointestinal tract of adult fasted rats, since the mechanisms responsible for protein wasting in these tissues are poorly understood. Protein mass of stomach, small intestine, and colon decreased by 14-29 and 21-49% after 1 and 5 days of fasting, respectively. The fractional rate of in vivo protein synthesis (ks) was approximately 34% lower in the stomach after 1 and 5 days of fasting due to decreased capacity for protein synthesis (Cs). In small intestine… CONTINUE READING