Gastrointestinal tract perforation in dogs treated with a selective cyclooxygenase-2 inhibitor: 29 cases (2002-2003).

@article{Lascelles2005GastrointestinalTP,
  title={Gastrointestinal tract perforation in dogs treated with a selective cyclooxygenase-2 inhibitor: 29 cases (2002-2003).},
  author={B Duncan X Lascelles and Anthony T Blikslager and Steven M. Fox and Doug Reece},
  journal={Journal of the American Veterinary Medical Association},
  year={2005},
  volume={227 7},
  pages={1112-7}
}
OBJECTIVE To identify factors associated with gastrointestinal tract perforation in dogs being treated with a selective cyclooxygenase-2 (COX-2) inhibitor (deracoxib). DESIGN Retrospective study. ANIMALS 29 dogs. PROCEDURE The Novartis Animal Health pharmacovigilance database was searched for records of dogs treated with deracoxib in which gastrointestinal tract perforation was documented. Results-16 of the 29 (55%) dogs had received deracoxib at a dosage higher than that approved by the… CONTINUE READING

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