Gastrointestinal tolerance of erythritol and xylitol ingested in a liquid

@article{Storey2007GastrointestinalTO,
  title={Gastrointestinal tolerance of erythritol and xylitol ingested in a liquid},
  author={D. M. Storey and A S Lee and Francis R. J. Bornet and Fred Brouns},
  journal={European Journal of Clinical Nutrition},
  year={2007},
  volume={61},
  pages={349-354}
}
Objectives:To determine and compare the gastrointestinal (GI) responses of young adults following consumption of 45 g sucrose, 20, 35 and 50 g xylitol or erythritol given as a single oral, bolus dose in a liquid.Design:The study was a randomized, double-blind, placebo-controlled study.Subjects:Seventy healthy adult volunteers aged 18–24 years were recruited from the student population of the University of Salford. Sixty-four subjects completed the study.Interventions:Subjects consumed at home… 
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References

SHOWING 1-10 OF 40 REFERENCES
Tolerance to subchronic, high-dose ingestion of erythritol in human volunteers.
TLDR
The results of the present study demonstrate that the repeated ingestion of erythritol at daily doses of 1 g/kg body wt was well tolerated by humans.
Laxative threshold of sugar alcohol erythritol in human subjects
Gastrointestinal response and plasma and urine determinations in human subjects given erythritol.
TLDR
It is demonstrated that ingestion of erythritol at doses of up to 0.8 g/kg body wt does not alter plasma or urine osmolarity or electrolyte balance and is well tolerated by the digestive tract.
Comparative gastrointestinal tolerance of sucrose, lactitol, or D-tagatose in chocolate.
TLDR
It is demonstrated that a 20-g dose of D-tagatose is tolerated well in comparison to lactitol, and is associated with a significant increase in the frequency of passing feces, or in the number of subjects passing watery feces, in a double-blind, controlled crossover study.
The comparative gastrointestinal response of young children to the ingestion of 25 g sweets containing sucrose or isomalt
TLDR
For the majority of children in the present study, 25 g isomalt-containing sweets represents an acceptable level of consumption, although some children are sensitive to the effects of isomALT ingestion.
Effects of oral administration of erythritol on patients with diabetes.
TLDR
The single dose study suggests that erythritol exerts no significant effects on the metabolism of diabetic patients and two-week daily administration of erystritol had no adverse effect on blood glucose control.
Oral xylitol in American adults
[Clinical tolerance, intestinal absorption, and energy value of four sugar alcohols taken on an empty stomach].
TLDR
Bacterial digestion of the sugar alcohols reaching the colon was complete, and did not affect healthy volunteers' clinical tolerance and energy value, according to their respective rates of digestion in the small intestine and the colon.
Metabolism of erythritol in humans: Comparison with glucose and lactitol
TLDR
It is concluded that erythritol is a substrate that is readily absorbed, and undergoes no metabolism by the host, and if part of it escapes absorption, it is not metabolized by faecal flora.
Tolerance to low-digestible carbohydrates: symptomatology and methods.
TLDR
There is an important intersubject variability in the tolerance to LDCs because of differences in absorption capacity, motility pattern, colonic response and intestinal sensitivity.
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