Gastrointestinal stromal tumour--a paradigm shift in management of solid tumours.

Abstract

Gastrointestinal stromal tumour (GIST) till recently were non-responsive to all chemotherapy agents. With the advent of c-kit, diagnosis of GIST has become more specific. STI-571, a tyrosine kinase, has become one of the first targeted therapeutic agent tobe active in solid tumour. At present it is the only agent with substantial activity in GIST. 

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Cite this paper

@article{Bapsy2003GastrointestinalST, title={Gastrointestinal stromal tumour--a paradigm shift in management of solid tumours.}, author={P. P. Bapsy and Kumar Prabhash and K. Ganapathi Babu and Meravanige Girish}, journal={The Journal of the Association of Physicians of India}, year={2003}, volume={51}, pages={801-4} }