Gastrointestinal stromal tumors. A review of characteristics morphologic, immunohistochemical, and molecular genetic features.

@article{Goldblum2002GastrointestinalST,
  title={Gastrointestinal stromal tumors. A review of characteristics morphologic, immunohistochemical, and molecular genetic features.},
  author={John R. Goldblum},
  journal={American journal of clinical pathology},
  year={2002},
  volume={117 Suppl},
  pages={
          S49-61
        }
}
Gastrointestinal stromal tumors are a heterogeneous group of neoplasms composed of either spindled or epithelioid cells that have distinctive histologic appearances and clinical behaviors in different portions of the gastrointestinal tract. These tumors are best evaluated in a site-specific manner, and prediction of clinical behavior is best achieved by evaluation of multiple characteristics, including cell type, cellularity, nuclear pleomorphism, mitotic counts, and the presence or absence of… CONTINUE READING